exercise induced asthma (eia) is a transient increase in airway resistance after intensive exercise and can be measured as a decline in forced expiratory volume in one second (fev1). the condition is due to increased training load and inhalation of cold and dry air. several studies have shown that eucapnic voluntary hyperpnea challenge test (evh test) is a very sensitive and specific diagnostic...

objective(s):bone marrow-derived mesenchymal stem cells (bmscs) have attracted significant interest to treat asthma and its complication. in this study, the effects of bmscs on lung pathology and inflammation in an ovalbumin-induced asthma model in mouse were examined. materials and methods:balb/c mice were divided into three groups: control group (animals were not sensitized), asthma group (an...

the prevalence of exercise induced asthma (eia) in iran is not known. in the present study the  prevalence of  eia  among female students  of  guidance school  in the  city of mashhad was evaluated. a total of 1690 female students aged 12-14 years in ten randomly selected schools in north east of iran (mashhad) completed an asthma symptoms- specific questionnaire. one hundred forty four randoml...

asthma is the most prevalent chronic disease in childhood. to determine the prevalence of asthma and related symptoms in children younger than 5 years, a survey was performed by interviewing mothers of 617 children during spring 2001. the interview comprised of two parts. the first part contained children characteristics including age, sex, maternal age at the child birth, child history of atop...

BACKGROUND Exercise induced asthma (EIA) plays an important role in clinical evaluation. There has been little previous work validating EIA as reported directly by children and indirectly by their parents. AIMS (1) To determine the strength of the association between children's symptoms of EIA and their physiological response to exercise in a laboratory setting. (2) To compare parents' percep...

Objective(s):Bone marrow-derived mesenchymal stem cells (BMSCs) have attracted significant interest to treat asthma and its complication. In this study, the effects of BMSCs on lung pathology and inflammation in an ovalbumin-induced asthma model in mouse were examined. Materials and Methods:BALB/c mice were divided into three groups: control group (animals were not sensitized), asthma group (an...

We have tested the effect of a porous cellulose fabric face mask. Nine asthmatic patients, anamnestically sensitive to cold, took part in exercise tests on an ergometer bicycle at a temperature of approximately -10 degrees C, with and without a face mask. For comparison, exercise tests were also performed with breathing taking place through a woolen scarf. Three minutes after finishing the exer...

Objective(s): Tanshinone IIA (T. IIA), one of the most pharmacologically active components extracted from Salviae miltiorrhiza, has anti-inflammatory and antioxidant features. The aim of the present study is to investigate the benefit of T. IIA on asthma using a murine model of asthma induced by ovalbumin (OVA). Materials and Methods: Male BALB/c mice were used in the present study. The mice we...

BACKGROUND A fall in FEV(1) of > or =10% following bronchoprovocation (eucapnic voluntary hyperventilation (EVH) or exercise) is regarded as the gold standard criterion for diagnosing exercise induced asthma (EIA) in athletes. Previous studies have suggested that mid-expiratory flow (FEF(50)) might be used to supplement FEV(1) to improve the sensitivity and specificity of the diagnosis. A study...